What Is Human Genome

This section provides a quick introduction of Human Genome, which is the complete set of genes packaged inside 23 chromosome pairs in the nuclei of each human cell.

What Is Human Genome? - Human Genome is the complete set of genes packaged inside 23 chromosome pairs in the nuclei of each human cell.

Human Genome is estimated to have between 20,000 and 25,000 genes, coded by 3,000,000,000 base pairs in DNA double helix structures.

What Is Human Karyotype? - Karyotype is a table of 23 chromosome pairs of the human genome lined up in the order of their sizes in 4 rows as shown below. The first 22 are called autosomes. The last one is called "Sex Chromosomes" which is a X-Y pair for male, and a X-X pair for female.

Chromosomes and Human Genome Karyotype
Chromosomes and Human Genome Karyotype

Note that in each human chromosome pairs, one chromosome is inherited from the mother, the other chromosome from the father.

Paired chromosomes, except sex chromosomes, are identical identical in size, shape, genes and gene positions. So each paired member is a mirror of the other member to back up each other.

Chromosome 1 in the first pair is the longest human chromosomes, which contains about 6,000 genes stored as a sequence of about 249,000,000 base pairs, which is actually a single strand of DNA double helix.

Chromosome 21 in the 21st pair is the shortest human chromosomes, which contains about 200 to 300 genes stored as a sequence of about 48,000,000 base pairs base pairs, which is actually a single strand of DNA double helix.

Table of Contents

 About This Book

 Introduction of Molecules

 Molecule Names and Identifications

 Molecule Mass and Weight

 Protein and Amino Acid

 Nucleobase, Nucleoside, Nucleotide, DNA and RNA

Gene and Chromosome

 What Is Gene

What Is Human Genome

 Gene Address on Chromosome

 DNA Coding and Codons

 Gene Expression - ­Building Proteins

 Genetic Transcription - Creating mRNA

 Genetic Translation - Creating Protein

 DNA Gene Sequence - Exons and Introns

 Chromosome Replication (or DNA Replication)

 Protein Kinase (PK)

 DNA Sequencing

 Gene Mutation

 SDF (Structure Data File)

 PyMol Installation

 PyMol GUI and CLI

 PyMol Selections

 PyMol Editing Functions

 PyMol Measurement Functions

 PyMol Movie Functions

 PyMol Python Integration

 PyMol Object Functions

 ChEMBL Database - European Molecular Biology Laboratory

 PubChem Database - National Library of Medicine

 PDB (Protein Data Bank)

 INSDC (International Nucleotide Sequence Database Collaboration)

 HGNC (HUGO Gene Nomenclature Committee)

 Relocated Tutorials

 Resources and Tools

 Molecule Related Terminologies

 References

 Full Version in PDF/EPUB