Molecule Tutorials - Herong's Tutorial Examples
∟Nucleobase, Nucleoside, Nucleotide, DNA and RNA
This chapter provides quick introductions about DNA and RNA and their building blocks: Nucleobases, Nucleosides, Nucleotides.
What Is Nucleobase
What Is Nucleoside
What Is Nucleotide
What Is Nucleic Acid
What Is RNA (Ribonucleic Acid)
What Is DNA (Deoxyribonucleic Acid)
RNA Primary Structure - Helix
DNA Primary Structure - Double Helix
What Is DNA/RNA Base and Sequence Pair
What Is Chromosome
Takeaways:
- There only 5 primary nucleobases found in nature that are used as information carriers
in DNA and RNA structures: Adenosine (A), Cytidine (C), Guanosine (G), Thymidine (T) and Uridine (U).
- A nucleoside is formed by a nucleobase and a 5-carbon sugar through a condenstation reaction.
- A nucleotide is formed by a nucleoside and a phosphate through a condenstation reaction.
- A nucleic acid is formed by a sequence of nucleotides through condenstation reactions
- The backbone of a nucleic acid is the linked sequence of sugar-phosphate residue pairs.
- Nucleobase residues in a nucleic acid are attached to sugar residues like leaves of the backbone.
- A RNA (Ribonucleic Acid) is a special nucleic acid that uses only riboses as sugars and 4 nucleobases:
Adenosine (A), Cytidine (C), Guanosine (G), and Uridine (U).
- A DNA (Deoxyribonucleic Acid) is a special nucleic acid that uses only deoxyriboses as sugars and 4 nucleobases:
Adenosine (A), Cytidine (C), Guanosine (G), and Thymidine (T).
- Single DNA/RNA sequence stays in a helix conformation as the primary structure.
- Two complementary DNA/RNA sequences becomes a sequence pair and
stays in a double helix conformation as the primary structure.
- A DNA/RNA double helix relies on their complementary nucleobases to form base pairs.
- A DNA/RNA base pair is pair of complementary nucleobases linked by hydrogen bonds.
Table of Contents
About This Book
Introduction of Molecules
Molecule Names and Identifications
Molecule Mass and Weight
Protein and Amino Acid
►Nucleobase, Nucleoside, Nucleotide, DNA and RNA
Gene and Chromosome
Protein Kinase (PK)
DNA Sequencing
Gene Mutation
SDF (Structure Data File)
PyMol Installation
PyMol GUI and CLI
PyMol Selections
PyMol Editing Functions
PyMol Measurement Functions
PyMol Movie Functions
PyMol Python Integration
PyMol Object Functions
ChEMBL Database - European Molecular Biology Laboratory
PubChem Database - National Library of Medicine
PDB (Protein Data Bank)
INSDC (International Nucleotide Sequence Database Collaboration)
HGNC (HUGO Gene Nomenclature Committee)
Relocated Tutorials
Resources and Tools
Molecule Related Terminologies
References
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